Public Comment on Request For Proposals and Selection Committee Nominations

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Public Comment on Request for Proposals and Selection Committee Nominations

Pursuant to the FY 2016-17 California state budget passed by the Legislature and expected to be signed by the Governor, we anticipate the California Initiative to Advance Precision Medicine (CIAPM) will receive an additional $10 million of funding. CIAPM is therefore planning to release a Request for Proposals (RFP) to select 6 proof-of-principal Demonstration Projects for support.  These projects will engage in broad collaborations between private, academic, non-profit and patient organizations to advance precision medicine in California.  Applicants to the RFP will have the opportunity to attend a CIAPM convening on August 26, 2016 in Los Angeles. This convening will provide an opportunity to help strengthen and build partnerships for the proposals, prior to final evaluation by the awards selection committee.


Public Comment on CIAPM Request for Proposals 2016

In anticipation of CIAPM releasing a Request for Proposals (RFP), we would like to solicit public input on any additional criteria that should be considered for inclusion into the RFP, in addition to those criteria that are required by statute.

Required criteria based on statutory language:

The guidelines for the award of funds must include:

  • Eligibility Requirements
  • A competitive, merit-based application process that allows public and private academic and non-profit institutions to submit proposals as principal investigators
  • A comprehensive peer-reviewed selection process
  • Requirements regarding the use of awarded funds
  • Requirements regarding the use and sharing of research data and findings
  • Requirements for the protection of privacy and personal health information.

Currently a Demonstration Project may focus on one or more disease areas, and shall be based on criteria that include, but are not limited to, the following:

  • The potential for tangible benefit to patients within two to five years, including the likelihood that the study will have an immediate impact on patients
  • The depth and breadth of data available in the disease focus areas across institutions
  • The prospects for efficient and effective data integration and analysis
  • The expertise of potential team members
  • The resources available for the project outside of the initiative, including the potential for leveraging non-state funding
  • The clinical and commercial potential of the project
  • The potential to reduce health disparities
  • The potential to scale and leverage multiple electronic health records systems
  • The potential to develop the use of tools, measurements, and data, including publicly generated and available data

Currently a Demonstration Project that is selected shall advance greater understanding in at least one of the following areas, or in another area that is determined to be necessary to advance precision medicine:

  • The application of precision medicine to specific disease areas
  • The challenges of system interoperability
  • Economic analysis
  • Standards for sharing data or protocols across institutions
  • The federal and state regulatory environment
  • The clinical environment
  • Challenges relating to data, tools, and infrastructure
  • The protection of privacy and personal health information
  • The potential for reducing health disparities
  • Methods and protocols for patient engagement

Request for public comment:

Please let us know if there are other criteria that should be considered to be included into the RFP. Comments may be submitted via email to ciapm@ucsf.eduResponses will be accepted through July 3, 2016. 

All responses will be tracked, reviewed and archived by CIAPM. CIAPM will consider all public input received through July 3rd before finalizing and releasing the RFP. CIAPM will use the information submitted in response to this request at its discretion and will not provide comments to any individual responder's submission. To protect privacy, CIAPM will not share specific comments, but CIAPM will post a summary of the comments received and the rationale for changes made in response to the comments.


Selection Committee Nominations

CIAPM will establish a precision medicine expert selection committee to review proposals submitted in response to CIAPM’s Request for Proposals 2016. The selection committee members must represent various precision medicine-related skills, including but not limited to: bioinformatics, statistics, health economics, patient engagement, and genomics. Selection committee members cannot have any interest in any contract related to this RFP. Selection committee members will be appointed based on their relevant training and experience, as well as service on prior review committees.

Request for nominations:

Please consider the specifications above when nominating individuals to serve on the selection committee. Please provide name, institutional affiliation, expertise, qualifications, and contact information for each nomination for serving on the selection committee.  Nominations may be submitted via email to ciapm@ucsf.eduNominations will be accepted through July 3, 2016. 

All nominations will be tracked, reviewed and archived by CIAPM.